Minimum Inhibitory Concentration Evaluator and Disc Diffusion Testing Techniques to Profile Antimicrobial Resistance in Arcobacterbutzleri

A. H. SHAH, G. S. BARHAM, G. B. KHASKHELI, M. A. JAMALI, N. A. KOREJO, Y. M. JALBANI, S. G. TUNIO

Abstract


The major objective of this study was to evaluate discrepancy in between two antibiotic susceptibility techniques, minimum inhibitory concentration evaluator (M.I.C.E) and disc diffusion. A total of 75AButzleriisolates were tested against ampicillin, tetracycline, ciprofloxacin, erythromycin, cefotaximeand gentamycin. The results revealed that 89.3% and 92% for ampicillin, 22.7% and 26.7% for ciprofloxacin,77.7% and 57.3% for erythromycin,9.4% and 13.3% for tetracycline, 53.3% and 73.3% for cefotaximeand 22.6% and 26.7% for gentamycin, isolates were resistant using M.I.C.E and disc diffusion, respectively. Moreover, multi-drug resistant was noticed in 16% by M.I.C.E and 12% by disc diffusion methods. Fisher’s analysis showed that both methods tested were non-significant (P≥0.05) for other antibiotics except erythromycin (P=0.0144) and cefotaxime (p=0.0173). In conclusion, tetracycline can be used as a drug of choice to treat infections caused by A. butzleriand either of the methods, disc diffusion or M.I.C.E, can be used for four of the six antibiotics tested.

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