ESTIMATION OF SERUM CHOLINESTERASE ACTIVITY OF OCCUPATIONALLY EXPOSED WORKERS OF A FERTILIZER PLANT

M. A. Shad, M. Aman ullah, R. Perveen

Abstract


In  the  present  study, serum  cholinesterase  activity was  measured in the sera of the workers of fertilizer plant and the people residing in the staff colony. Carbon dioxide, ammonia, nitric  acid and phosphoric acid are synthesized for the manufacturing  of  urea, nitrophos  and  calcium  ammonium  nitrate in the fertilizer plant. The activity of the enzyme found to be decreased in the workers and residents who were exposed directly or indirectly to the different gaseous emissions and waste products produced during different chemical processes compared to unexposed subjects. It is therefore suggested that the monitoring of serum cholinesterase activity can serve as a measure of an occupational exposure of  workers  of  the  fertilizer  plants  and can also be used as biomarker to monitor the toxicity of gaseous emissions and waste products.


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